Article
Blastic plasmacytoid dendritic cell neoplasm with genetic mutations in multiple epigenetic modifiers: a case report.
The Journal of international medical research - 1 Feb 2021
Dang Xinmei, Zhou Di, Meng Lingjun, Bi Lintao
Abstract excerpt
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematodermic malignancy derived from plasmacytoid dendritic cell precursors. Despite advances in our understanding of tumor cell surface markers, the pathogenesis of BPDCN remains largely unknown. No standard or optimal treatments are available for BPDCN, and the prognosis is usually poor. We report herein a case of BPDCN that harbored...
Topics
- Dendritic Cells
- Epigenesis, Genetic
- Hematologic Neoplasms
- Humans
- Mutation
- Myeloproliferative Disorders
- Skin Neoplasms