Article
HLA-G susceptibility to hepatitis B infection and related hepatocellular carcinoma in the Japanese population.
Human immunology - 1 Aug 2023
Okumura Taiki, Joshita Satoru, Yamazaki Tomoo, Iwadare Takanobu, Wakabayashi Shun-Ichi, Kobayashi Hiroyuki, Yamashita Yuki, Sugiura Ayumi, Kimura Takefumi, Ota Masao, Umemura Takeji
Abstract excerpt
AIMS: Human leukocyte antigen (HLA)-G plays a role in various physiological immunomodulatory functions. Aberrant HLA-G expression is observed in various disease states, including tumors, autoimmune disorders, and viral infections. The present study investigated the association between HLA-G functional gene polymorphisms (rs1736933 [-486 C > A], rs1049033 [+2018 C > T], 14 bp Insertion [Ins]/Deletion [Del] [+2961...
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