Article
HLA-G genetic variants and hepatocellular carcinoma: a meta-analysis.
Genetics and molecular research : GMR - 26 Aug 2016
Coelho A V C, Moura R R, Crovella S, Celsi F
Abstract excerpt
Human leukocyte antigen (HLA)-G is a key tolerogenic molecule mainly expressed in the placenta and is crucial for implantation of the embryo and immunological tolerance of the fetus during pregnancy. However, under pathological conditions, such as cancer or viral infections, HLA-G can be expressed in other tissues. The gene coding for HLA-G (HLA-G, chromosome 6p21.3) presents numerous polymorphisms, some of them...
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