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Article

KIR2DL4/HLA-G polymorphisms were associated with HCV infection susceptibility among Chinese high-risk population.

Journal of medical virology - 1 Mar 2023

Feng Zepei, Huang Peng, Zhang Jinwei, Xia Xueshan, Zhang A-Mei, Zeng Tian, Chen Qiong, Zhu Chuanlong, Tan Weilong, Zhang Yun, Yue Ming

Abstract excerpt

Killer-cell immunoglobulin-like receptors 2DL4 (KIR2DL4) and the human leukocyte antigen class I-G (HLA-G) display vital parts in immune responses against hepatitis C virus (HCV) infection. We select four potentially functional single nucleotide polymorphisms (SNPs) of KIR/HLA to explore the associations between KIR2DL4/HLA-G genetic variants and HCV infection results. In the present case-control study, a total...

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PMID: 36890645
DOI: 10.1002/jmv.28645

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