Article
Genetic polymorphisms of the HLA-DP and HLA-DQ genes could influence Hepatitis B virus infection in Yunnan population.
Immunological investigations - 1 Jan 2021
Song Yuzhu, Xia Tian, Xia Xueshan, Zhang A-Mei
Abstract excerpt
Hepatitis B, caused by hepatitis B virus (HBV) infection, is one of the epidemic and infectious hepatitis diseases. The sigle-nucleotide polymorphisms were identified to associate with HBV infection in East Asian population by genome-wide association study (GWAS), but no study in Yunnan HBV population was reported. We recruited 493 HBV patients and 460 general controls to genotype 7 GWAS SNPs, and then, the...
Topics
- Alleles
- China
- Disease Susceptibility
- Gene Frequency
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genotype
- HLA-DP Antigens
- HLA-DQ Antigens
- Hepatitis B
- Hepatitis B virus
- Humans
- Polymorphism, Single Nucleotide
- Population Surveillance
