Article
Association of HLA-G 3'UTR polymorphisms with hepatitis B virus infection in Tunisian population.
Immunologic research - 1 Oct 2024
Laaribi Ahmed Baligh, Mehri Asma, Yahia Hamza Ben, Chaouch Houda, Babay Wafa, Letaief Amel, Ouzari Hadda-Imene, Hannachi Naila, Boukadida Jalel, Zidi Ines
Abstract excerpt
Hepatitis B virus (HBV) infection is a major public health burden. The mechanisms of immune evasion during chronic HBV (CHB) infection are poorly understood. Human leukocyte antigen (HLA)-G, an immune checkpoint molecule, plays a crucial role in the tolerance mechanisms of various infectious diseases. The 3' untranslated region (3'UTR), including the HLA-G + 3142 C > G polymorphism (rs1063320) and the 14-pb...
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