Article
Human Leukocyte Antigen Class II Alleles Are Associated with Hepatitis C Virus Natural Susceptibility in the Chinese Population.
International journal of molecular sciences - 23 Jul 2015
Yue Ming, Xu Ke, Wu Meng-Ping, Han Ya-Ping, Huang Peng, Peng Zhi-Hang, Wang Jie, Su Jing, Yu Rong-Bin, Li Jun, Zhang Yun
Abstract excerpt
Human leukocyte antigen (HLA) class II molecule influences host antigen presentation and anti-viral immune response. The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) within HLA class II gene were associated with different clinical outcomes of hepatitis C virus (HCV) infection. Three HLA class II SNPs (rs3077, rs2395309 and rs2856718) were genotyped by TaqMan assay among...
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