Article
Genetic polymorphism of HLA-DQ confers susceptibility to hepatitis B virus-related hepatocellular carcinoma: a case-control study in Han population in China.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2016
Gao Xia, Liu Wenxuan, Zhang Xiaolin, Tang Longmei, Wang Liqin, Yan Lina, Yang Haitao, Li Tao, Yang Lei, Ma Ning, Liu Dianwu
Abstract excerpt
Several recent genome-wide studies showed that the genetic polymorphisms in the HLA-DQ region (rs9275572 and rs2856718) were related to chronic hepatitis B virus (HBV) infection and chronic hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC). We analyzed the two single-nucleotide polymorphisms for major HBV outcomes in Han Chinese. A total of 1291 samples were involved and peripheral blood samples...
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