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Article

The contributions of mitochondrial and nuclear mitochondrial genetic variation to neuroticism.

Nature communications - 30 May 2023

Xia Charley, Pickett Sarah J, Liewald David C M, Weiss Alexander, Hudson Gavin, Hill W David

Abstract excerpt

Neuroticism is a heritable trait composed of separate facets, each conferring different levels of protection or risk, to health. By examining mitochondrial DNA in 269,506 individuals, we show mitochondrial haplogroups explain 0.07-0.01% of variance in neuroticism and identify five haplogroup and 15 mitochondria-marker associations across a general factor of neuroticism, and two special factors of anxiety/tension,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37253732
DOI: 10.1038/s41467-023-38480-y
PMCID: PMC10229642

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