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mef2ca and mef2cb Double Mutant Zebrafish Show Altered Craniofacial Phenotype and Motor Behaviour.

Biomolecules - 9 May 2023

Adrião Andreia, Mariano Sara, Mariano José, Gavaia Paulo J, Cancela M Leonor, Vitorino Marta, Conceição Natércia

Abstract excerpt

The transcription factor MEF2C is crucial in neuronal, cardiac, bone and cartilage molecular processes, as well as for craniofacial development. MEF2C was associated with the human disease MRD20, whose patients show abnormal neuronal and craniofacial development. Zebrafish mef2ca;mef2cb double mutants were analysed for abnormalities in craniofacial and behaviour development through phenotypic analysis....

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Identifiers

PMID: 37238675
DOI: 10.3390/biom13050805
PMCID: PMC10216501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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