Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression.

BMC developmental biology - 7 Jun 2006

Nissen Robert M, Amsterdam Adam, Hopkins Nancy

Abstract excerpt

BACKGROUND: Craniofacial birth defects result from defects in cranial neural crest (NC) patterning and morphogenesis. The vertebrate craniofacial skeleton is derived from cranial NC cells and the patterning of these cells occurs within the pharyngeal arches. Substantial efforts have led to the identification of several genes required for craniofacial skeletal development such as the endothelin-1 (edn1) signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Conserved Sequence
Share to Craniofacial Abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelin-1

Share to Neural Crest

Share to Nuclear Proteins

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 16759393
DOI: 10.1186/1471-213X-6-28
PMCID: PMC1523201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression.PMID 16759393Read ↗

Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates.Semantic proximity Read ↗

Understanding endothelin-1 function during craniofacial development in the mouse and zebrafish.Semantic proximity Read ↗

Loss-of-function of Endothelin receptor type A results in Oro-Oto-Cardiac syndrome.Semantic proximity Read ↗

A morpholino‐based screen to identify novel genes involved in craniofacial morphogenesisSemantic proximity Read ↗

A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development.Semantic proximity Read ↗

Requirements for Endothelin type-A receptors and Endothelin-1 signaling in the facial ectoderm for the patterning of skeletogenic neural crest cells in zebrafish.Semantic proximity Read ↗

Functional analysis of ESRP1/2 gene variants and CTNND1 isoforms in orofacial cleft pathogenesis.Semantic proximity Read ↗

Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11.Semantic proximity Read ↗

Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice.Semantic proximity Read ↗

Elucidating timing and function of endothelin-A receptor signaling during craniofacial development using neural crest cell-specific gene deletion and receptor antagonism.Semantic proximity Read ↗

A non-syndromic orofacial cleft risk locus links tRNA splicing defects to neural crest cell pathologies.Semantic proximity Read ↗

Regulated extracellular matrix trafficking shapes cell growth during cartilage morphogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.