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Article

Zebrafish as a Model to Investigate Dynamin 2-Related Diseases.

Scientific reports - 4 Feb 2016

Bragato Cinzia, Gaudenzi Germano, Blasevich Flavia, Pavesi Giulio, Maggi Lorenzo, Giunta Michele, Cotelli Franco, Mora Marina

Abstract excerpt

Mutations in the dynamin-2 gene (DNM2) cause autosomal dominant centronuclear myopathy (CNM) and dominant intermediate Charcot-Marie-Tooth (CMT) neuropathy type B (CMTDIB). As the relation between these DNM2-related diseases is poorly understood, we used zebrafish to investigate the effects of two different DNM2 mutations. First we identified a new alternatively spliced zebrafish dynamin-2a mRNA (dnm2a-v2) with...

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Source

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Identifiers

PMID: 26842864
DOI: 10.1038/srep20466
PMCID: PMC4740890

Genes

DNM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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