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Article

mef2ca is required in cranial neural crest to effect Endothelin1 signaling in zebrafish.

Developmental biology - 1 Aug 2007

Miller Craig T, Swartz Mary E, Khuu Patricia A, Walker Macie B, Eberhart Johann K, Kimmel Charles B

Abstract excerpt

Mef2 genes encode highly conserved transcription factors involved in somitic and cardiac mesoderm development in diverse bilaterians. Vertebrates have multiple mef2 genes. In mice, mef2c is required for heart and vascular development. We show that a zebrafish mef2c gene (mef2ca) is required in cranial neural crest (CNC) for proper head skeletal patterning. mef2ca mutants have head skeletal phenotypes resembling...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17574232
DOI: 10.1016/j.ydbio.2007.05.018
PMCID: PMC2148033

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