Article
Requirements of myocyte-specific enhancer factor 2A in zebrafish cardiac contractility.
FEBS letters - 29 Aug 2005
Wang Yue-Xiang, Qian Lin-Xi, Yu Zhang, Jiang Qiu, Dong Yong-Xin, Liu Xue-Fei, Yang Xin-Ying, Zhong Tao P, Song Hou-Yan
Abstract excerpt
Myocyte-specific enhancer factor 2A (MEF2A) regulates a broad range of fundamental cellular processes including cell division, differentiation and death. Here, we tested the hypothesis that MEF2A is required in cardiac contractility employing zebrafish as a model organism. MEF2A is highly expressed in heart as well as somites during zebrafish embryogenesis. Knock-down of MEF2A in zebrafish impaires the cardiac...
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