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Article

Sex differences in the polygenic architecture of hearing problems in adults.

Genome medicine - 11 May 2023

De Angelis Flavio, Zeleznik Oana A, Wendt Frank R, Pathak Gita A, Tylee Daniel S, De Lillo Antonella, Koller Dora, Cabrera-Mendoza Brenda, Clifford Royce E, Maihofer Adam X, Nievergelt Caroline M, Curhan Gary C, Curhan Sharon G, Polimanti Renato

Abstract excerpt

BACKGROUND: Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predisposition. Although several risk loci have been already identified, HP biology and epidemiology are still insufficiently investigated by large-scale genetic studies. METHODS: Leveraging the UK...

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Identifiers

PMID: 37165447
DOI: 10.1186/s13073-023-01186-3
PMCID: PMC10173489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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