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Article

Polygenic Risk Score-Based Association Analysis Identifies Genetic Comorbidities Associated with Age-Related Hearing Difficulty in Two Independent Samples.

Journal of the Association for Research in Otolaryngology : JARO - 1 Aug 2024

Bhatt Ishan Sunilkumar, Raygoza Garay Juan Antonio, Bhagavan Srividya Grama, Ingalls Valerie, Dias Raquel, Torkamani Ali

Abstract excerpt

PURPOSE: Age-related hearing loss is the most common form of permanent hearing loss that is associated with various health traits, including Alzheimer's disease, cognitive decline, and depression. The present study aims to identify genetic comorbidities of age-related hearing loss. Past genome-wide association studies identified multiple genomic loci involved in common adult-onset health traits. Polygenic risk...

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Identifiers

PMID: 38782831
DOI: 10.1007/s10162-024-00947-0
PMCID: PMC11349729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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