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Article

Discovering Age- and Sex-Specific Genetic Risk Factors in Sensorineural Hearing Loss: Genome-Wide Evidence from Large-Scale Biobanks.

Journal of the Association for Research in Otolaryngology : JARO - 1 Aug 2026

Bizaki-Vallaskangas Argyro, Sliz Eeva, Lankinen Tuuli, Saarentaus Elmo, Salo Ville, Krebs Kristi, Willberg Tytti, Kivekäs Ilkka, Rämö Joel, Toppila-Salmi Sanna, Dietz Aarno, Hytönen Vesa, Palotie Aarno, Milani Lili, Mäkitie Antti, Kettunen Johannes

Abstract excerpt

PURPOSE: Investigate the genetic components of sensorineural hearing loss (SNHL) by performing genome-wide meta-analyses using the data from FinnGen and Estonian Biobank. METHODS: We studied genome-wide associations of SNHL in FinnGen and the Estonian Biobank in the general population and in sex- and age-of-onset stratified subgroups. The study-specific GWASs were combined through inverse variance-weighted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42192083
DOI: 10.1007/s10162-026-01054-y
PMCID: PMC13504140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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