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Article

Polygenic Contribution to Sensorineural Hearing Loss Implicates Novel Risk Loci and Convergence with Congenital Hearing Loss Genes.

Journal of the Association for Research in Otolaryngology : JARO - 1 Jun 2026

Clifford Royce E, Johnson Jacquelyn A, Mackey Caroline E, Mikita Elizabeth A, Ryan Allen F, Maihofer Adam X, Nievergelt Caroline M

Abstract excerpt

PURPOSE: Disabling sensorineural hearing loss (SNHL) affects 5% of the global population. While congenital (CHL) and non-congenital sensorineural hearing loss (SNHL) are both strongly heritable, SNHL is a polygenic disorder, consisting of common genetic variants which individually confer small risks, requiring large studies for significance. METHODS: We present the first report of a SNHL genome-wide association...

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Identifiers

PMID: 41840298
DOI: 10.1007/s10162-026-01044-0
PMCID: PMC13237364

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MVP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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