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Genomic Scar Score: A robust model predicting homologous recombination deficiency based on genomic instability

1 Nov 2022

Abstract excerpt

OBJECTIVE: To develop a novel machine learning-based algorithm called the Genomic Scar Score (GSS) for predicting homologous recombination deficiency (HRD) events. DESIGN: Method development study. SETTING: AmoyDx Medical Laboratory and Jiangsu Cancer Hospital. POPULATION OR SAMPLE: A cohort of individuals with ovarian or breast cancer (n = 377) were collected from the AmoyDx Medical Laboratory. Another cohort of...

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PMID: 36485068
DOI: 10.1111/1471-0528.17324

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