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Article

In-depth proteomics reveals the characteristic developmental profiles of early lung adenocarcinoma with epidermal growth factor receptor mutation.

Cancer medicine - 1 May 2023

Dai Tomoko, Adachi Jun, Dai Yuichi, Nakano Noriyuki, Yamato Mariko, Kikuchi Shinji, Usui Shingo, Minami Yuko, Tomonaga Takeshi, Noguchi Masayuki, Matsubara Daisuke, Sakamoto Noriaki

Abstract excerpt

INTRODUCTION: Lung adenocarcinoma progresses stepwise from atypical adenomatous hyperplasia to adenocarcinoma in situ (AIS), followed by minimally invasive adenocarcinoma (MIA), and then obvious invasive adenocarcinoma. In this study, we examined the protein expression profiles of early and epidermal growth factor receptor (EGFR) mutation-positive lung adenocarcinomas. METHODS: Fifteen cases of small and EGFR...

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Identifiers

PMID: 37004157
DOI: 10.1002/cam4.5766
PMCID: PMC10225231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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