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Evolutionary proteogenomic landscape from pre-invasive to invasive lung adenocarcinoma

1 Jan 2024

Abstract excerpt

Lung adenocarcinoma follows a stepwise progression from pre-invasive to invasive. However, there remains a knowledge gap regarding molecular events from pre-invasive to invasive. Here, we conduct a comprehensive proteogenomic analysis comprising whole-exon sequencing, RNA sequencing, and proteomic and phosphoproteomic profiling on 98 pre-invasive and 99 invasive lung adenocarcinomas. The deletion of chr4q12...

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PMID: 38183982
DOI: 10.1016/j.xcrm.2023.101358

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