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Article

Integrative proteomic characterization of human lung adenocarcinoma with KRAS G12 mutations reveals molecular pathogenesis.

Journal of advanced research - 1 Jun 2026

Shi Xinyu, Hu Liling, Huang Yongshi, Zhang Mei-Fang, Ying Xingfeng, Yuan Xiaoyi, Wen Nengqiao, Lu Jiangli, Zou Hanchen, Tan Xiaohui, He Qing-Yu, Wang Fang, Yang Hong, Zhang Chris Zhiyi

Abstract excerpt

INTRODUCTION: Integrated proteogenomic studies of lung adenocarcinoma (LUAD) have provided unique insights with potential clinical effects. Comprehensive proteomic analyses are needed to better understand the molecular landscape of LUAD with KRAS G12 mutations. OBJECTIVES: This study aims to characterize the proteogenomic profile of LUAD with KRAS G12 mutation variants. METHODS: We performed next-generation...

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Share to Adenocarcinoma of Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40957478
DOI: 10.1016/j.jare.2025.09.014
PMCID: PMC13227296

Genes

KRAS
SLC4A7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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