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Article

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations.

Molecular oncology - 1 Nov 2025

Bugyi Fanni, Balbisi Mirjam, Sugár Simon, Váncza Lóránd, Regős Eszter, Kovalszky Ilona, Laczó Ibolya, Harkó Tünde, Kecskeméti Gábor, Szabó Zoltán, Moldvay Judit, Drahos László, Turiák Lilla

Abstract excerpt

Genetic alterations in key oncogenes have been frequently identified in lung adenocarcinoma (LUAD), including genes encoding epidermal growth factor receptor (EGFR), Kirsten rat sarcoma viral oncogene homolog (KRAS), and anaplastic lymphoma kinase (ALK). In this pilot study, we aimed to characterize the differences in enriched biological pathways and phosphorylation events between LUAD tumors harboring EGFR,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40621945
DOI: 10.1002/1878-0261.70091
PMCID: PMC12591317

Genes

EGFR
ALK
KRAS
EML4
CDK2
SRSF1
SRSF2
SRSF7

Provenance

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