Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proteogenomic characterization reveals tumorigenesis and progression of lung cancer manifested as subsolid nodules

11 Mar 2025

Abstract excerpt

Lung adenocarcinoma (LUAD) radiologically displayed as subsolid nodules (SSNs) is prevalent. Nevertheless, the precise clinical management of SSNs necessitates a profound understanding of their tumorigenesis and progression. Here, we analyze 66 LUAD displayed as SSNs covering 3 histological stages including adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA) and invasive adenocarcinoma (IAC) by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Phylogenetic Studies
Share to Lung Cancer Treatments and Mutations
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40069142
DOI: 10.1038/s41467-025-57364-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteogenomic characterization reveals tumorigenesis and progression of lung cancer manifested as subsolid nodulesPMID 40069142Read ↗

Evolutionary proteogenomic landscape from pre-invasive to invasive lung adenocarcinomaSemantic proximity Read ↗

Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures.Semantic proximity Read ↗

Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression.Semantic proximity Read ↗

Proteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissuesSemantic proximity Read ↗

Integrated multi-omic analysis and experiment reveals the role of endoplasmic reticulum stress in lung adenocarcinomaSemantic proximity Read ↗

Integrated whole-exome and bulk transcriptome sequencing delineates the dynamic evolution from preneoplasia to invasive lung adenocarcinoma featured with ground-glass nodules.Semantic proximity Read ↗

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma.Semantic proximity Read ↗

Multiomics Analysis Reveals Molecular Changes during Early Progression of Precancerous Lesions to Lung Adenocarcinoma in Never-Smokers.Semantic proximity Read ↗

Proteomic Analyses Identify Differentially Expressed Proteins and Pathways Between Low-Risk and High-Risk Subtypes of Early-Stage Lung Adenocarcinoma and Their Prognostic ImpactsSemantic proximity Read ↗

Mechanisms of Progression and Heterogeneity in Multiple Nodules of Lung AdenocarcinomaSemantic proximity Read ↗

A proteogenomic portrait of lung squamous cell carcinoma.Semantic proximity Read ↗

Proteogenomic characterization identifies clinical subgroups in EGFR and ALK wild-type never-smoker lung adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.