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Article

A sex-stratified analysis of the genetic architecture of human brain anatomy.

Nature communications - 13 Sept 2024

Shafee Rebecca, Moraczewski Dustin, Liu Siyuan, Mallard Travis, Thomas Adam, Raznahan Armin

Abstract excerpt

Large biobanks have dramatically advanced our understanding of genetic influences on human brain anatomy. However, most studies have combined rather than compared male and female participants. Here we screen for sex differences in the common genetic architecture of over 1000 neuroanatomical phenotypes in the UK Biobank and establish a general concordance between male and female participants in heritability...

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Identifiers

PMID: 39271676
DOI: 10.1038/s41467-024-52244-2
PMCID: PMC11399304

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