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Article

CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

1 Mar 2023

Abstract excerpt

Inflammatory responses are crucial for controlling infections and initiating tissue repair. However, excessive and uncontrolled inflammation causes inflammatory disease. Processing and release of the pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18 depend on caspase-1 activation within inflammasomes. Assembly of inflammasomes is initiated upon activation of cytosolic pattern recognition receptors...

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Share to Gout, Hyperuricemia, Uric Acid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36930645
DOI: 10.1016/j.celrep.2023.112265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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