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Research Progress on the Role of Inflammasomes in Kidney Disease

29 Jan 2020

Abstract excerpt

Inflammasomes are multimeric complexes composed of cytoplasmic sensors, apoptosis-associated speck-like protein containing a caspase activation and recruitment domain (ASC or PYCARD), and procaspase-1 and play roles in regulating caspase-dependent inflammation and cell death. Inflammasomes are assembled by sensing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) and...

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PMID: 32410864
DOI: 10.1155/2020/8032797

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