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Article

The role of NLRP12 in inflammatory diseases

10 Aug 2023

Abstract excerpt

Nucleotide-binding leucine-rich repeat-containing receptor 12 (NLRP12), a highly conserved protein containing an N-terminal pyrin domain (PYD), a nucleotide-binding domain and a C-terminal leucine-rich repeat region, belongs to the nucleotide-binding oligomerization domain-like receptor-containing PYD (NLRP) family and is a cytoplasmic sensor that plays a negative role in inflammation. NLRP12 is involved in...

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Identifiers

PMID: 37572944
DOI: 10.1016/j.ejphar.2023.175995

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