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Article

Regulation and Sensing of Inflammasomes and Their Impact on Intestinal Health

2017-10-25

Abstract excerpt

Pattern recognition receptors such as nucleotide-binding oligomerization domain (NOD)-containing protein receptors (NLRs) and the pyrin and HIN domain (PYHIN) receptors initiate the inflammatory response following cell stress or pathogenic challenge. When activated some of these receptors oligomerize to form the structural backbone of a signalling platform known as the inflammasome. The inflammasome promotes the a...

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Identifiers and source

Literature Corpus work
b47a44a5-bf51-5909-85c7-33cb76d8361a
DOI
10.20944/preprints201710.0160.v1
Open publication

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