Article
NLRP7: From inflammasome regulation to human disease.
Immunology - 1 Aug 2021
Carriere Jessica, Dorfleutner Andrea, Stehlik Christian
Abstract excerpt
Nucleotide-binding oligomerization domain (NOD) and leucine-rich repeat (LRR)-containing receptors or NOD-like receptors (NLRs) are cytosolic pattern recognition receptors, which sense conserved microbial patterns and host-derived danger signals to elicit innate immune responses. The activation of several prototypic NLRs, including NLR and pyrin domain (PYD) containing (NLRP) 1, NLRP3 and NLR and caspase...
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