Article
SUMOylation of Wor1 by a novel SUMO E3 ligase controls cell fate in Candida albicans.
Molecular microbiology - 1 Oct 2015
Yan Minghui, Nie Xinyi, Wang Huafeng, Gao Ning, Liu Haoping, Chen Jiangye
Abstract excerpt
Candida albicans is the most common human fungal pathogen, yet is a normal commensal resident of the human gut. CO(2) levels in the gut are much higher than in air, and it is known that elevated CO(2) concentration promotes C. albicans cells to undergo a phenotypic switch from white to opaque phase. Wor1, the master regulator of opaque cell formation, is required for both the white to opaque transition and opaque...
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