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Article

Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes.

Genetic epidemiology - 1 Jun 2023

Shoaib Muhammad, Ye Qiang, IglayReger Heidi, Tan Meng H, Boehnke Michael, Burant Charles F, Soleimanpour Scott A, Gagliano Taliun Sarah A

Abstract excerpt

Polygenic risk scores (PRS) quantify the genetic liability to disease and are calculated using an individual's genotype profile and disease-specific genome-wide association study (GWAS) summary statistics. Type 1 (T1D) and type 2 (T2D) diabetes both are determined in part by genetic loci. Correctly differentiating between types of diabetes is crucial for accurate diagnosis and treatment. PRS have the potential to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36821788
DOI: 10.1002/gepi.22521
PMCID: PMC10202843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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