Article
Systematic Review of Polygenic Risk Scores for Type 1 and Type 2 Diabetes.
International journal of molecular sciences - 2 Mar 2020
Padilla-Martínez Felipe, Collin Francois, Kwasniewski Miroslaw, Kretowski Adam
Abstract excerpt
Recent studies have led to considerable advances in the identification of genetic variants associated with type 1 and type 2 diabetes. An approach for converting genetic data into a predictive measure of disease susceptibility is to add the risk effects of loci into a polygenic risk score. In order to summarize the recent findings, we conducted a systematic review of studies comparing the accuracy of polygenic...
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