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Article

Evaluating the Efficacy of Type 2 Diabetes Polygenic Risk Scores in an Independent European Population.

International journal of molecular sciences - 17 Jan 2024

Brīvība Monta, Atava Ivanna, Pečulis Raitis, Elbere Ilze, Ansone Laura, Rozenberga Maija, Silamiķelis Ivars, Kloviņš Jānis

Abstract excerpt

Numerous type 2 diabetes (T2D) polygenic risk scores (PGSs) have been developed to predict individuals' predisposition to the disease. An independent assessment and verification of the best-performing PGS are warranted to allow for a rapid application of developed models. To date, only 3% of T2D PGSs have been evaluated. In this study, we assessed all (n = 102) presently published T2D PGSs in an independent...

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Identifiers

PMID: 38256224
DOI: 10.3390/ijms25021151
PMCID: PMC10817091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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