Article
STS loaded PCL-MECM based hydrogel hybrid scaffolds promote meniscal regeneration via modulating macrophage phenotype polarization.
Biomaterials science - 11 Apr 2023
Li Muzhe, Yin Han, Chen Mingxue, Deng Haotian, Tian Guangzhao, Guo Weimin, Yi Guoliang, Guo Quanyi, Chen Zhiwei, Liu Shuyun
Abstract excerpt
Meniscus injury has a limited ability to heal itself and often results in the progression to osteoarthritis. After a meniscus injury, there is an obvious acute or chronic inflammatory response in the articular cavity, which is not conducive to tissue regeneration. M2 macrophages are involved in tissue repair and remodeling. Regenerative medicine strategies for tissue regeneration by enhancing the phenotypic ratio...
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