Article

Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophages

2020-08-22

Abstract excerpt

Aberrant extracellular matrix (ECM) assembly surrounding implanted biomaterials is the hallmark of the foreign body response, in which implants become encapsulated in thick fibrous tissue that prevents their proper function. While macrophages are known regulators of fibroblast behavior, how their phenotype influences ECM assembly and the progression of the foreign body response is poorly understood. In this study,...

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Literature Corpus work: b37bb2b6-c651-535e-b64a-483d8226cbfe
DOI: 10.1101/2020.08.21.261933

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