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Article

Effects of the fibrous topography-mediated macrophage phenotype transition on the recruitment of mesenchymal stem cells: An in vivo study.

Biomaterials - 1 Dec 2017

Zhang Qiankun, Hwang Jin Wook, Oh Joung-Hwan, Park Chan Ho, Chung Shin Hye, Lee Yun-Sil, Baek Jeong-Hwa, Ryoo Hyun-Mo, Woo Kyung Mi

Abstract excerpt

Host responses to a biomaterial critically influence its in vivo performance. Biomaterial architectures that can recruit endogenous host stem cells could be beneficial in tissue regeneration or integration. Here, we report that the fibrous topography of biomaterials promotes the recruitment of host mesenchymal stem cells (MSCs) by facilitating the macrophage phenotype transition from M1-to-M2. Electrospun poly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29017079
DOI: 10.1016/j.biomaterials.2017.10.007

Genes

CCR7
MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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