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Article

Transdermal Transfersome Nanogels Control Hypertrophic Scar Formation via Synergy of Macrophage Phenotype-Switching and Anti-Fibrosis Effect.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Feb 2024

Chen Yunsheng, Chen Kun, Zhong Shan, Wang Jiaqiang, Yu Zhixi, Sun Xiyang, Wang Yue, Liu Yan, Zhang Zheng

Abstract excerpt

Hypertrophic scar (HS), which results from prolonged inflammation and excessive fibrosis in re-epithelialized wounds, is one of the most common clinical challenges. Consequently, sophisticated transdermal transfersome nanogels (TA/Fu-TS) are prepared to control HS formation by synergistically inhibiting inflammation and suppressing fibrosis. TA/Fu-TSs have unique structures comprising hydrophobic triamcinolone...

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Identifiers

PMID: 38064170
DOI: 10.1002/advs.202305468
PMCID: PMC10870058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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