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Article

Unsaturated polyurethane films grafted with enantiomeric polylysine promotes macrophage polarization to a M2 phenotype through PI3K/Akt1/mTOR axis.

Biomaterials - 1 Jul 2020

Duan Yiyuan, Zheng Honghao, Li Zehua, Yao Yuejun, Ding Jie, Wang Xuemei, Nakkala Jayachandra Reddy, Zhang Deteng, Wang Zhaoyi, Zuo Xingang, Zheng Xiaowen, Ling Jun, Gao Changyou

Abstract excerpt

The immune system responds immediately to tissue trauma and to biomaterial implants under the participation of M1/M2 macrophages polarization. The surface properties of biomaterials can significantly influence the tissue repair progress through modulating the macrophage functions. In this study, the surface of poly(propylene fumarate) polyurethane films (PPFU) is grafted with a same density of enantiomeric...

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PMID: 32276198
DOI: 10.1016/j.biomaterials.2020.120012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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