Enhanced Bone Regeneration via Dual Immune-Modulatory Scaffold: Integrating Lipopolysaccharide/Gelatin Methacrylate and Proanthocyanidins/Polylactic Acid to Enhance Macrophage Recruitment and M2 Phenotype Polarization.

Abstract excerpt

The initiation of bone repair inherently involves inflammation, a key regulator of the healing cascade. However, uncontrolled or excessive inflammation can hinder the natural bone repair process. By modulating the immune response, focusing particularly on macrophage recruitment and polarization, the injury microenvironment can be transformed by facilitating conditions more conducive to rapid bone regeneration....

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• Bone Regeneration
• Gelatin
• Lipopolysaccharides
• Mesenchymal Stem Cells
• Osteogenesis