Article

The impact of biomaterial characteristics on macrophage phenotypes in tissue engineering: a review

2025-04-30

Abstract excerpt

Macrophages are highly plastic cells central to pathogen removal, tissue regeneration, and inflammation, making them key targets in biomaterial design for improved clinical outcomes. Foreign body responses (FBRs) to implanted biomaterials often involve excessive macrophage-mediated inflammation, leading to fibrotic encapsulation, infection, and implant failure. Advances in tissue engineering demonstrate that macro...

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Literature Corpus work: e1f8d70f-3061-5e9f-acd9-1e3a8af581c4
DOI: 10.20517/2347-9264.2024.166

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