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Article

Polygenic Risk Scores for Alzheimer's Disease and General Cognitive Function Are Associated With Measures of Cognition in Older South Asians.

The journals of gerontology. Series A, Biological sciences and medical sciences - 11 May 2023

Zhao Wei, Smith Jennifer A, Wang Yi Zhe, Chintalapati Manjusha, Ammous Farah, Yu Miao, Moorjani Priya, Ganna Andrea, Gross Alden, Dey Sharmistha, Benerjee Joyita, Chatterjee Prasun, Dey Aparajit B, Lee Jinkook, Kardia Sharon L R

Abstract excerpt

Genome-wide association studies (GWAS) conducted in European ancestry (EA) have identified hundreds of single-nucleotide polymorphisms (SNPs) associated with general cognitive function and/or Alzheimer's disease (AD). The association between these SNPs and cognitive function has not been fully evaluated in populations with complex genetic substructure such as South Asians. This study investigated whether SNPs...

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Identifiers

PMID: 36782352
DOI: 10.1093/gerona/glad057
PMCID: PMC10172981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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