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Article

Affordable drug resistance genotyping of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings.

AIDS research and therapy - 9 Feb 2023

Manyana Sontaga, Pillay Melendhran, Gounder Lilishia, Khan Aabida, Moodley Pravi, Naidoo Kogieleum, Chimukangara Benjamin

Abstract excerpt

BACKGROUND: As use of dolutegravir (DTG) becomes more common in resource limited settings (RLS), the demand for integrase resistance testing is increasing. Affordable methods for genotyping all relevant HIV-1 pol genes (i.e., protease (PR), reverse transcriptase (RT) and integrase (IN)) are required to guide choice of future antiretroviral therapy (ART). We designed an in-house HIV-1 drug resistance (HIVDR)...

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Identifiers

PMID: 36759801
DOI: 10.1186/s12981-023-00505-3
PMCID: PMC9912687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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