Article
HIV-1 Drug Resistance Genotyping in Resource Limited Settings: Current and Future Perspectives in Sequencing Technologies.
Viruses - 11 Jun 2021
Manyana Sontaga, Gounder Lilishia, Pillay Melendhran, Manasa Justen, Naidoo Kogieleum, Chimukangara Benjamin
Abstract excerpt
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses use of Sanger sequencing and next generation sequencing (NGS) methods for HIV-1 drug resistance (HIVDR) genotyping, focusing on their use in resource limited settings (RLS). Sanger sequencing remains the gold-standard method for...
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