Article
Field evaluation of a broadly sensitive HIV-1 in-house genotyping assay for use with both plasma and dried blood spot specimens in a resource-limited country.
Journal of clinical microbiology - 1 Feb 2013
Inzaule Seth, Yang Chunfu, Kasembeli Alex, Nafisa Lillian, Okonji Jully, Oyaro Boaz, Lando Richard, Mills Lisa A, Laserson Kayla, Thomas Timothy, Nkengasong John, Zeh Clement
Abstract excerpt
HIV-1 drug resistance (HIVDR) assays are important tools in clinical management of HIV-infected patients on antiretroviral therapy (ART) and surveillance of drug-resistant variants at population levels. The high cost associated with commercial assays hinders their use in resource-limited settings. We adopted and validated a low-cost in-house assay using 68 matched plasma and dried blood spot (DBS) samples with a...
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