Article
An HIV-1 integrase genotype assay for the detection of drug resistance mutations.
Sexual health - 1 Dec 2009
Hearps Anna C, Greengrass Vicki, Hoy Jennifer, Crowe Suzanne M
Abstract excerpt
BACKGROUND: The integrase inhibitors (e.g. Raltegravir) are a new class of antiretroviral drugs that have recently become available for the treatment of patients with multi-drug resistant HIV-1 within Australia. The emergence of mutations that confer resistance to the integrase inhibitors has been observed in vivo; however, no commercial genotyping assay is currently available to screen for resistance to these...
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