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Article

Comparison of an in-house 'home-brew' and commercial ViroSeq integrase genotyping assays on HIV-1 subtype C samples.

PloS one - 1 Jan 2019

Seatla Kaelo K, Choga Wonderful T, Mogwele Mompati, Diphoko Thabo, Maruapula Dorcas, Mupfumi Lucy, Musonda Rosemary M, Rowley Christopher F, Avalos Ava, Kasvosve Ishmael, Moyo Sikhulile, Gaseitsiwe Simani

Abstract excerpt

BACKGROUND: Roll-out of Integrase Strand Transfer Inhibitors (INSTIs) such as dolutegravir for HIV combination antiretroviral therapy (cART) in sub-Saharan Africa necessitates the development of affordable HIV drug resistance (HIVDR) assays targeting the Integrase gene. We optimised and evaluated an in-house integrase HIV-1 drug resistance assay (IH-Int) and compared it to a commercially available assay, ViroSeq™...

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Identifiers

PMID: 31751353
DOI: 10.1371/journal.pone.0224292
PMCID: PMC6871785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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