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Article

PNPLA3 Genotype and Diabetes Identify Patients With Nonalcoholic Fatty Liver Disease at High Risk of Incident Cirrhosis.

Gastroenterology - 1 May 2023

Chen Vincent L, Oliveri Antonino, Miller Matthew J, Wijarnpreecha Karn, Du Xiaomeng, Chen Yanhua, Cushing Kelly C, Lok Anna S, Speliotes Elizabeth K

Abstract excerpt

BACKGROUND & AIMS: Non-alcoholic fatty liver disease (NAFLD) can progress to cirrhosis and hepatic decompensation, but whether genetic variants influence the rate of progression to cirrhosis or are useful in risk stratification among patients with NAFLD is uncertain. METHODS: We included participants from 2 independent cohorts, they Michigan Genomics Initiative (MGI) and UK Biobank (UKBB), who had NAFLD defined...

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Identifiers

PMID: 36758837
DOI: 10.1053/j.gastro.2023.01.040
PMCID: PMC10550206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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