Article
Genetic risk of fatty liver disease and mortality in the general population: A Mendelian randomization study.
Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2023
Gellert-Kristensen Helene, Tybjaerg-Hansen Anne, Nordestgaard Børge G, Ghouse Jonas, Fuchs Andreas, Kühl Jørgen T, Sigvardsen Per E, Kofoed Klaus F, Stender Stefan
Abstract excerpt
BACKGROUND & AIMS: Fatty liver disease has been associated with higher all-cause as well as liver-related, ischemic heart disease (IHD)-related and extrahepatic cancer-related mortality in observational epidemiological studies. We tested the hypothesis that fatty liver disease is a causal risk factor for higher mortality. METHODS: We genotyped seven genetic variants known to be associated with fatty liver disease...
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