Article
Mutational profile, outcomes, and impact of allogeneic hematopoietic stem cell transplantation in adult patients with acute myeloid leukemia and inconclusive cytogenetic analysis.
European journal of haematology - 1 Jun 2023
Vasudevan Nampoothiri Ram, Tang Kenny, Schuh Andre, Lam Wilson, Maze Dawn, Michelis Fotios V, Chan Steven, Gupta Vikas, Kim Dennis, Kumar Rajat, Lipton Jeffrey Howard, Mattsson Jonas, Minden Mark, Schimmer Aaron, Sibai Hassan, Viswabandya Auro, Yee Karen, Murphy Tracy, Law Arjun D
Abstract excerpt
BACKGROUND: Inconclusive cytogenetic analysis (IC) at baseline has been reported as a predictor of poor prognosis in patients with acute myeloid leukemia (AML). The mutational profile in this group of patients, and its impact on outcomes have not been reported. METHODS: We retrospectively analyzed adult patients (≥18 years) with newly diagnosed AML treated with intensive induction chemotherapy between 2015 and...
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